Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was developed and is being marketed by the pharmaceutical company Pfizer. It acts by inhibiting c GMP specific phosphodiesterase type 5, an enzyme that regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra). Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer's Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). The first clinical trials were conducted in Morriston Hospital in Swansea. Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a child's condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily. If you are taking sildenafil to treat erectile dysfunction, you should know that it does not cure erectile dysfunction or increase sexual desire. Sildenafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Amoxicillin uses and dosage Buy aciclovir 5 cream Oct. 19, 2007 -- The FDA is alerting men taking the erectile dysfunction drugs Cialis, Levitra, and Viagra of the potential risk of sudden hearing. Sudden hearing loss SHL is a significant hearing loss that occurs in 72 hours or of some agents that affect blood flow -- largely increase it --, such as sildenafil Viagra and Tidalafil. A new study suggests men who take Viagra or similar drugs for erectile dysfunction may double their chances of hearing impairment. Here, I will log my hopefully successful recovery from acute inner ear damage that occured last week. I believe supplements and some drug abuse might've played a role, so I'm looking to get any opinions or clues from more experienced members. I have learned a lot from this forum, but until this accident, I didn't have much to contribute. Two ENT specialists were confused and didn't help much, other than prescribing a drug and scheduled a checkup next month. Me31, male, active and leading a happy, low-stress life. In reasonably good shape, currently perhaps 20% BF, naturally athletic. No serious health issues until now, except bad teenage acne and tiny patches of vitiligo that isn't spreading. Incident A week ago, during a set of squats, I began to feel dizzy and short of breath. Gym was terribly ventilated that day, so I rushed to a window to regain my composure. (SHL) is defined as greater than 30 d B hearing reduction, over at least three contiguous frequencies, occurring over 72 hours or less. It occurs most frequently in the 30 to 60 year age group and affects males and females equally. Although called sudden, it seems unlikely that hearing loss is abrupt but rather it probably evolves over a few hours. SHL is usually unilateral (that is, it affects only one ear); and is often accompanied by tinnitus, aural fullness, vertigo, or any combination. The amount of hearing loss may vary from mild to severe, and may involve different parts of the hearing frequency range. About one third of people with SHL awaken in the morning with a hearing loss. A discussion of sudden bilateral hearing loss is found here. SHL also should be "sensorineural" meaning that it is not caused by a mechanical process such as ear wax (which causes a "conductive" loss). Our experience is that most patients who complain of "sudden hearing loss" actually have ear wax impactions. Looking in the ear canal is the usual way these people are quickly identified. These people are not "diagnosed" as SHL, although they do have sudden -- hearing -- loss. Sildenafil hearing loss Viagra vs. Sildenafil What's The Difference?, Sudden Hearing Loss Metoprolol itchingBuy diflucan in canada Sildenafil has been associated with rare instances of clinically apparent liver injury. Background. Rare, but potentially serious adverse events include vision and hearing loss, hypotension. SILDENAFIL. Viagra may double hearing loss risk Health24. Ups and Downs of Viagra Revisiting Ototoxicity in the Mouse Model. The study found 47 cases of hearing loss associated with taking this class of who are concerned that they have had side effects from sildenafil and other PDR-5 inhibitors tadlafil and. Since the recent death of Playboy editor-and-chief Hugh Heffner, the topic of hearing loss as a side effect of taking the prescription Viagra has. There is still a degree of hearing loss in higher frequencies, probably 40-50 dB if my home tests can be trusted. Sildenafil was probably long gone from the system. I can't find any information if such delayed action would be typical or not.