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    Sildenafil is used in the treatment of Erectile Dysfunction . Erectile dysfunction is the inability to achieve or maintain an erection long enough to perform sexual intercourse. Headache, flushing, respiratory tract infection, angina pectoris, AV block, migraine, syncope, tachycardia, postural hypotension, MI, cerebral thrombosis, cardiac arrest, paraesthesia, tremor, depression, herpes simplex, skin ulcer, oesophagitis, abnormal LFT, rectal haemorrhage, hypoglycaemic reaction, arthritis, deafness, retinal vascular disease, photosensitivity, accidental fall. Metabolism: Metabolised in the liver mainly by CYP3A4 and CYP2C9. Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. Potentially Fatal: May potentiate hypotensive effects of of organic nitrates and nicorandil. Patients concurrently or intermittently using organic nitrates in any form. Excretion: Excreted as metabolites mainly in the faeces. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Sildenafil inhibits phosphodiesterase type-5 (PDE5) which is responsible for c GMP degradation in the corpus cavernosum. Caution when used in patients with anatomical deformation of penis or conditions that may predispose them to priapism (e.g. Mild, transient, dose-related impairment of colour discrimination (blue/green) may occur. Inhibition of PDE5 increases c GMP levels in the corpus cavernosum which results in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Hepatic or severe renal impairment, bleeding disorders, active peptic ulceration, hypotension, recent history of stroke, MI, arrhythmias, unstable angina, heart failure or retinal disorders. Sildenafil citrate is the active ingredient in Viagra 50 MG Tablet, which is informally also known as the "blue pill". It is primarily used for the treatment of erectile dysfunction (ED), which is also called impotence, in men. Erectile dysfunction is a condition where a man is unable to achieve and/or maintain a penile erection adequate enough for sexual intercourse. It happens when there is a decreased blood flow to the penis. The decreased blood flow may be due to physical complications following an injury or disease or due to some psychological conditions such as anxiety, stress, depression, etc. Chronic lifestyle factors such as obesity, smoking, drinking, etc., could also contribute to ED. ED is strongly age-related, and the occurrence of moderate-to-severe ED could increase two-fold to three-fold between the ages of 40 and 70 years.

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    This medication is a phosphodiesterase type 5 (PDE5) inhibitor, prescribed for erectile dysfunction (impotence). If you have been told not to have sex by your doctor. It relaxes the blood vessels in the penis, allowing more blood to enter to achieve an erection. Erectile dysfunction is the inability to achieve or maintain an erection long enough to perform sexual intercourse. Pulmonary Arterial Hypertension- 20 mg 3 times daily. If you think there was an overdose, call your local poison control center or ER right away. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. It can also be used in pulmonary arterial hypertension. It relaxes the blood vessels in the penis, allowing more blood to enter to achieve an erection. It comes as a tablet to take by mouth and injection to be administered through a vein. IV- 10 mg (12.5 m L) administered as a bolus injection 3 times daily. Wearing layers of clothes or summer clothes and staying in cool places may help. It can also be used in pulmonary arterial hypertension. To treat pulmonary arterial hypertension it is usually taken three times a day. If you use drugs called poppers like amyl nitrite and butyl nitrite. Erectile dysfunction is the inability to achieve or maintain an erection long enough to perform sexual intercourse. Do not take 2 doses at the same time or extra doses. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. Drugs for Erectile Dysfunction This medication is a phosphodiesterase type 5 (PDE5) inhibitor, prescribed for erectile dysfunction (impotence). If it is close to the time for your next dose, skip the missed dose and go back to your normal time. If you have an allergy to sildenafil or any other part of this drug. Make sure to tell about the allergy and what signs you had. Avoid Alcohol Store in a cool, dry place away from the reach of children. Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester. The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website. The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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