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    The A-Z of this medication for the treatment of acne Isotretinoin has revolusionised the treatment of acne since it became available in South Africa in 1984, according to the National Dermatology Working Group led by Dr Dave Presbury. It is the only treatment that affects all four aetiological factors implicated in the acne process namely: Isotretinoin can also be prescribed for other conditions: Seborrhoea, Gram-negative folliculitis, Rosacea, and Hidradentis suppurativa. More and more patients are failing to respond to long-term antibiotics, both topical creams or tablets. This is due to the increase in resistance of P.acnes to many antibiotics. Studies have shown that even people with mild to moderate acne may develop scars for which long-term management remains a problem. Scarring from acne may have long-term physical and emotional ramifications. Other treatments are slower in onset of action, and scarring may occur before they take effect. This leaflet answers some common questions about ROACCUTANE. It does not take the place of talking to your doctor or pharmacist. Your doctor has weighed the risks of you taking ROACCUTANE against the benefits they expect it will have for you. ROACCUTANE contains the active ingredient isotretinoin. Retinoids work by reducing the amount of the oily substance (i.e. If you have any concerns about taking this medicine, ask your doctor or pharmacist. sebum) made by glands in your skin, reducing bacteria and inflammation and opening clogged pores. ROACCUTANE belongs to a group of medicines called retinoids, which are similar to vitamin A. There are many different types of medicines used to treat acne. Your doctor, however, may have prescribed ROACCUTANE for another purpose. Ask your doctor if you have any questions about why ROACCUTANE has been prescribed for you. This medicine is available only with a doctor's prescription. If you are not sure if you should start taking ROACCUTANE, contact your doctor. ROACCUTANE may be associated with slowing of growth when used in children before puberty. The use of ROACCUTANE in children less than 12 years of age is not recommended.

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