Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI). Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Duloxetine is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Duloxetine is also used in adults to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain). Duloxetine is also used to treat pain caused by nerve damage in adults with diabetes (diabetic neuropathy). Do not take duloxetine within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Report any new or worsening symptoms to your doctor. Duloxetine belongs to the class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). It is used to treat depression and generalized anxiety disorder. It can also be used to treat diabetes-related nerve pain, fibromyalgia, chronic low back pain, and chronic pain from osteoarthritis of the knee. For depression and anxiety, duloxetine works by affecting the balance of chemicals in the brain and other parts of the body. For certain types of pain, duloxetine works by affecting the balance of chemicals in the brain and spinal cord that are involved in the experience of pain. This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. Valacyclovir vs acyclovir for shingles Doxycycline rash treatment Jun 18, 2018. Learn about warnings, side effects, dosage, and more for duloxetine. mg given as 20-mg doses twice daily or 60 mg given either once daily. Find information about which conditions Duloxetine Oral is commonly used to treat. Skip to main content. What Conditions does Duloxetine HCL Treat? Repeated Episodes of Anxiety; Duloxetine DR Capsules. Dosage Form. Capsule. NDC# 43547-379-06. Strength. 20 mg. Size. 60 Count. Reference Listed Drug. Cymbalta® Product Shelf Life. 24 months Endo Pharmaceuticals recently announced the availability of Belbuca, the first buccal formulation of buprenorphine FDA approved for pain. Belbuca is the first and currently the only formulation of buprenorphine that can be delivered by dissolving a film which is placed on the inner lining of the cheek carrying an indication for chronic pain. Buprenorphine didn’t get its start as a treatment for pain. On the surface, this might look like just another one of those pharmaceutical gimmicks that puts a flashy new formulation on the market to rehash an already available medication. Rather, it was initially thought to be helpful for reducing cravings for patients that have an opioid abuse disorder. Buprenorphine is a partial agonist at the mu-opioid receptor (responsible for opioid’s euphoric effects) and as such leads to a less robust euphoric response…voila – less abuse potential! Not long after, researchers discovered buprenorphine has some excellent analgesic qualities as well. The safety profile of buprenorphine presents an additional benefit compared to traditional full agonist opioids, as buprenorphine has a “ceiling effect.” This dramatically reduces the risk of opioid-induced respiratory depression – the common causative factor of opioid overdose-related death due to the partial agonist activity. Opioids block the carbon dioxide feedback loop that is used to stimulate the respiratory center in the brainstem to increase respiratory rate. Duloxetine was approved for the treatment of major depression in 2004. While duloxetine has demonstrated improvement in depression-related symptoms compared to placebo, comparisons of duloxetine to other antidepressant medications have been less successful. A 2012 Cochrane Review did not find greater efficacy of duloxetine compared to SSRIs and newer antidepressants. Additionally, the review found evidence that duloxetine has increased side effects and reduced tolerability compared to other antidepressants. It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. do not list duloxetine among the recommended treatment options. A review from the Annals of Internal Medicine lists duloxetine among the first line drug treatments, however, along with citalopram, escitalopram, sertraline, paroxetine, and venlafaxine. Duloxetine dr 20mg Duloxetine Oral Uses, Side Effects, Interactions, Pictures, Warnings., Conditions that Duloxetine Oral Treats - WebMD Does amoxicillin treat utiSildenafil for heart failureClomid mexicoXanax kidney disease CYMBALTA is available as delayed release capsules 20 mg opaque green capsules imprinted with “Lilly 3235 20mg” 30 mg opaque white and blue capsules imprinted with “Lilly 3240 30mg” 60 mg opaque green and blue capsules imprinted with “Lilly 3270 60mg” Storage And Handling Cymbalta Duloxetine Hcl Side Effects, Interactions.. Duloxetine DR Capsules - Solco Healthcare. Cymbalta Duloxetine Hcl Patient Information Side Effects and Drug.. Cymbalta received an overall rating of 6 out of 10 stars from 1081 reviews. My Dr knew I was an alcoholic when he prescribed me the medication but failed to. DULOXETINE HYDROCHLORIDE 20 MG- duloxetine capsule, delayed release DULOXETINE HYDROCHLORIDE 30 MG- duloxetine capsule, delayed release DULOXETINE HYDROCHLORIDE 60 MG- duloxetine capsule, delayed release Number of versions 1 See full prescribing information for duloxetine delayed-release. Duloxetine is available as delayed release capsules 20 mg opaque green capsules.